AlfaCenterAI
Models that learn the rules of biology from data at scale.
Applied AI research center
Building AIfor humanhealth.
We work at the intersection of machine learning, biomedicine, and engineering.
Working programs in cardiovascular risk and sleep, and a long bet on genomic prognosis.
CardiovascularSleepGenomic prognosis
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Index
The programs.
Each is an independent system built around one clinical question. Cardiovascular risk and sleep are where the work has gone furthest.
01–03
Where the work has gone furthest.
Cardiovascular risk and sleep are the two programs where our work has gone furthest. AlfaDiscovery is the longer bet.
What we do
Applied AI, built to work in practice.
AlfaCenter is an applied AI research center at the intersection of machine learning, biomedicine, and engineering. We organize our work as a set of independent projects, each built around a specific scientific problem.
Machine learning
Foundation models, agentic reasoning and predictive systems built to be validated, not just demoed.
Biomedicine
Oncology, cardiovascular disease, sleep, neurodegeneration and more, grounded in real clinical questions.
Engineering
Automation systems, robotics and physical AI that turn research into systems that work in practice.
AlfaCore: a world model for human health
Signalsmolecules → whole person
- GenomicDNA & polygenic variation
- MolecularBiomarkers & blood chemistry
- CellularSingle-cell & embryology
- ImagingCT, MRI & retinal scans
- PhysiologicalWearables, vitals & sleep
- ClinicalHistory & medical records
- EnvironmentalAir, lifestyle & exposome
AlfaCore
Digital human twin
Predict
- Disease risk
- Therapy response
Generate
- Polygenic risk scores
- Care pathways
Simulate
- Virtual trials
- Health trajectories
AlfaCore is a world model for human health that connects signals across every scale, from molecules to the whole person. The system predicts, generates and simulates health outcomes, modeling the behavior of a virtual patient.
Specialized research directions.
Healthcare & life sciences
Alfa Life
Cardiovascular prediction, sleep physiology, neurodegeneration, ophthalmology, reproductive medicine, drug discovery and digital human twins.
Cardiovascular predictionSleep physiologyNeurodegenerationOphthalmologyReproductive medicineDrug discoveryDigital human twins
Agentic & physical AI
Alfa Agent
Geospatial intelligence, biogas systems, automation and robotics. Agentic and physical AI that turns research into systems that work.
Geospatial intelligenceBiogas systemsAutomationRobotics
From AI foundations to the clinic.
Foundation models
Pretrained biological models adapted across many tasks.
Neuromedicine
Brain and nervous-system disease modeling.
Multi-omics
Genome, transcriptome, proteome and more.
Single cell
Resolving biology one cell at a time.
Cancer
Decoding tumor biology toward precision oncology.
Drug discovery
From target to candidate, computationally guided.
Let’s build AI for human health.
Researchers, clinicians and partners. We’d love to talk.